Medycyna Wet. 62 (9), 1059-1060, 2006
Krakowska I., Jaworska-Adamu J.
Expression of estrogen receptors α in parahippocampal gyrus following 17β estradiol application in female rabbits
The aim of the study was to determine the localization of estrogen receptors α in the parahippocampal gyrus (gyrus parahippocampalis) following 17β application in ovariectomized rabbits. Studies were carried out using an immunocytochemical method. Estrogen receptors α immunoreactivity in neurons and astrocytes were detected in the cellular layers of parasubiculum, perisubiculum and entorhinalis region. However ERα immunoreactivity was not detected in astrocytes ovariectomized rabbits in the experimental group where there was no E2 application. On the other hand, the neurons showed very weak colorization. The results obtained indicate that the structure of rabbit parahippocampal gyrus is under the influence of estrogen, which causes an increase in ERα expression.
Keywords: estrogen receptors α, hippocampal gyrus, rabbit