Medycyna Wet. 64 (10), 1191-1195, 2008
Hukowska-Szematowicz B., Deptuła W.
Theoretical and practical aspects of the RNA interference phenomenon
The discovery of the RNA interference phenomenon proved to be a significant breakthrough in determining the mechanism in which the flow of genetic information is controlled. Apart from dsRNA and siRNA, also microRNA molecules are involved in the process. Current data prove that the phenomenon of RNA interference will open new perspectives in the therapy of numerous diseases, including metabolic, cancer, neurodegenerative and viral ones.
Key words: RNA interference phenomenon, double-stranded RNA (dsRNA), microRNA (miRNA), small interfering RNA (siRNA)