Medycyna Wet. 66 (8), 525-529, 2010
Minta M., Stypuła-Trębas S.
Endocrine disruptors in the environment: a risk to public health?
Many chemicals to which humans are regularly exposed can interfere with hormonal functions and induce adverse health effects. Some “old” synthetic chemicals (DDT, PCBs, dioxins, diethylstilbestrol, bisphenol A, atrazine and tributyltin) have had the clearest link to an impact on wild animals. It has been hypothesized that in humans these compounds may be responsible for the increased incidence of breast and testicular cancer as well as for reproductive disorders. During the last decades much concern has been focused on new groups of chemicals such as brominated flame retardants, phthalates, perfluorinated chemicals, parabens and veterinary drugs (anabolics). Food and drinking water are the main routes of exposure. These substances generally occur at nontoxic concentrations, but a major medical challenge is exposure to their mixtures.
Key words: endocrine disruptors, environment, public health