Medycyna Wet. 67 (2), 129-132, 2011
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Niedźwiedź A., Nicpoń J., Borowicz H., Łoś P., Zawadzki M., Januszewska L.
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Evaluation of selected antioxidant enzymes in the blood of horses with recurrent airways obstruction
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The aim of this study was to evaluate the activity of antioxidant enzymes in horses diagnosed with recurrent airway obstruction (RAO). The study was conducted on a group of 40 horses, various breeds, divided into two groups, aged 8-15 years, including 15 males and 25 mares. Blood was collected for antioxidant analyses from 20 recurrent airway obstruction (RAO)-affected horses and 20 healthy control horses. The authors determined the activity of glutathione reductase, glutathione peroxidase and glutathione S-transferase in the blood. Average reductase activity in a group of healthy horses was 79.7 U / g, while in the group of RAO-affected horses it was 39.7 U / g. The average activity of glutathione peroxidase in the group of healthy horses was 47.8 U / g, while in the group of RAO-affected horses it was 37.8 U / g. The average activity of glutathione S-transferase in the group of healthy horses was 39.8 U / g, while in the group of RAO-affected horses it was 21.8 U / g. The resulting research indicates that oxidative stress is a consequence of chronic airway inflammation in the course of RAO in horses.
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Key words: horses, RAO, oxidative stress
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