Medycyna Wet. 67 (2), 129-132, 2011

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Niedźwiedź A., Nicpoń J., Borowicz H., Łoś P., Zawadzki M., Januszewska L.
Evaluation of selected antioxidant enzymes in the blood of horses with recurrent airways obstruction
The aim of this study was to evaluate the activity of antioxidant enzymes in horses diagnosed with recurrent airway obstruction (RAO). The study was conducted on a group of 40 horses, various breeds, divided into two groups, aged 8-15 years, including 15 males and 25 mares. Blood was collected for antioxidant analyses from 20 recurrent airway obstruction (RAO)-affected horses and 20 healthy control horses. The authors determined the activity of glutathione reductase, glutathione peroxidase and glutathione S-transferase in the blood. Average reductase activity in a group of healthy horses was 79.7 U / g, while in the group of RAO-affected horses it was 39.7 U / g. The average activity of glutathione peroxidase in the group of healthy horses was 47.8 U / g, while in the group of RAO-affected horses it was 37.8 U / g. The average activity of glutathione S-transferase in the group of healthy horses was 39.8 U / g, while in the group of RAO-affected horses it was 21.8 U / g. The resulting research indicates that oxidative stress is a consequence of chronic airway inflammation in the course of RAO in horses.
Key words: horses, RAO, oxidative stress