Medycyna Wet. 64 (4b), 546-550, 2008
Siemieniuch M. J., Bogacki M., Skarżyński D. J., Wocławek-Potocka I.
Differences between species in maternal recognition of pregnancy in mammals
The maternal recognition of pregnancy in mammals is based on the communication between embryo/fetus, uterus and corpus luteum. The development and maintenance of the gestation needs a great deal of physiological adaptations in females, especially in the immunological system. In ruminants IFNt has a basic meaning for the maternal recognition of pregnancy. IFNt is an antyluteolitic factor produced by mononuclear cells in the trophoblast and ensure the communication between the female and the developing embryo. However, in pigs IFNt secretion is not a factor of pregnancy recognition and the communication between the mother and embryos may be conducted by estrogens at about 10-11 days of gestation and the change in PGF2a secretion. Up until now interferone produced by trophoblasts has not been observed in horses. Pregnancy maintenance and embryo development depends on the embryo migration in the uterus lumen before implantation. Little is known about maternal recognition signals of pregnancy in carnivores. The only thing that has been confirmed is elevated concentrations of acute phase proteins (C-reactive protein, haptoglobin, fibrinogen, seromucoid, ceruloplasmine, glikoproteins) detected in pregnant bitches’ serum.
Keywords: maternal recognition of pregnancy, interferon tau, prostaglandins, corpus luteum