Medycyna Wet. 64 (4b), 541-545, 2008
Kaczmarek M. M., Blitek A., Kowalczyk A. E., Kiewisz J., Waclawik A., Ziecik A. J.
Role of integrins, extracellular matrix proteins and growth factors during early implantation in pigs
Successful embryo implantation in pigs, as in other domestic species, requires synchronized dialogue between the uterus and embryo. Trofoblast attachment to the uterine epithelium is mediated by adhesion molecules (i.e. integrins and extracellular matrix proteins). Both embryonic and endometrial production of various growth factors and their receptors’ expression are essential for proper embryo development and implantation. This review will discuss their role as possible markers of endometrial receptivity in pigs.
Keywords: implantation, integrins, extracellular matrix proteins, growth factors, pig