Medycyna Wet. 67 (9), 584-588, 2011
Truszczyński M., Pejsak Z.
PRRS – achievements of the past years and priorities of present and future research
Among other important research areas and discoveries the nature of the genomic diversity of porcine reproductive and respiratory syndrome virus (PRRSV) has been presented. This phenomenon was evaluated as an essential factor of the difficulties in obtaining effective live attenuated vaccines against PRRS, covering cross protection against the existing variants. Cell-lines for the isolation of the virus and seroneutralization were mentioned. These assays were evaluated in comparison with tests for the detection of nucleic acids of the genome and viral proteins for diagnostic purposes that proved to be more rapid than virus isolation and seroneutralization. Primarily ELISA was discussed among serological tests identifying specific antibodies. In the second part of this review of literature, as priorities among present and future research projects, procedures acting against the transmission of PRRSV infection from pig to pig, including semen used for artificial insemination, and against transmission of the virus from farm to farm were discussed. Improvement of disinfection methods and facilities as well as selection of effective disinfectants were added as present and future research projects. Among future topics the evaluation of air filters was also included. The necessity of the improvement of post-vaccinal immunity was emphasized in connection with the improvement of the efficacy of vaccines. The evaluation of the infection of dams in herds with highly pathogenic strains of the PRRSV originating from the region of the farm was also mentioned, including gilt acclimatization.
Keywords: porcine reproductive and respiratory syndrome, present and future research priorities