Med. Weter. 70 (3), 157-160, 2014

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Bukowska D., Kempisty B., Ciesiółka S., Piotrowska H., Antosik P., Jaśkowski J.M., Nowicki M.
Role of hormones and growth factors in implantation of embryo in mammals
The implantation belongs to the most crucial steps of processes involved in proper derived pregnancy as well as normal embryo development. The synchronization of interaction between embryo and endometrium is regulated by the processes of reaching the endomentrial place of implantation by embryos and achieving of proper developmental capacity by blastocyst. Process of implantation is divided into three stages of; apposition, adhesion and invasion. The systems that regulates proper course of these mechanisms are based on secretion of hormones and synthesis of selected growth factors. The disturbances in these factors-derived signaling pathways leads to lack of implantations and/or abortion. Moreover, as the results of these disrupted mechanisms, the decreased fertility potential, is also included. In this review, the molecular basics of embryos implantation, was presented. This knowledge may be used in the future in the recipients diagnostics and estimation of possibility of embryos attachment used in embryo-transfer in many species of mammals.
Key words: implantation, hormones, embryo, growth factors.