Med. Weter. 71 (10), 595-598, 2015
full text
| Truszczyński M., Pejsak Z. |
| Present state of research on Glässer’s disease of swine |
| The introduction of this review of literature contains basic data of Glässer’s disease occurring in swine and boar. This is followed by the characterization of the properties of Haemophilus (H.) parasuis and the pathogenesis. Information about at least 15 classified serovars, using immunodiffusion testing or passive hemagglutination, is given. Potentially pathoghenic strains belong to serovar: 1, 5, 10, 12, 13 and 14. However, this classification shows exceptions, indicating that not all strains of the mentioned serovars, even of serovar 5, are pathogenic. On the other side strains, not belonging to the so called pathogenic serovars, cause Glässer’s disease. The recent developments of genomic information and genetic manipulation systems have improved the selection of virulent H. parasuis strains, contributing to better understanding of the pathogenesis of H. parasuis infection. Some data are presented how the pathogen overcomes host immune responses, with participation of virulence factors coded by defined genes. The cited results, concerning genes and pathogenicity factors of H. parasuis contribute also to improvement of the efficacy of the vaccine against Glässer’s disease. Finally prevention and control of Glässer’s disease is presented. |
| Key words: Glässer’s disease, basic data, Haemophilus parasuis, pathogenesis, virulence factors, prevention, control |