Med. Weter. 75 (11), 684-692, 2019
full text
OMER GURKAN DILEK, ROSEN STEFANOV DIMITROV,
KAMELIA DIMCHEVA STAMATOVA-YOVCHEVA,
DAVID GOSPODINOV YOVCHEV, RADOSLAV MIHAYLOV |
Importance for experiments in human medicine
of imaging modalities for macroanatomical and
histological study of rabbit suprarenal glands |
The morphological characteristics of the rabbit adrenal glands are currently investigated using routine
imaging modalities. The aim of the study was to collect and interpret major findings and information in the
literature on the rabbit as an animal model for investigations in humans. The suprarenal glands of thirty-four
mature, clinically healthy New Zealand rabbits were studied using anatomical, routine histology, radiology,
computed tomography, ultrasonography, and magnetic resonance imaging methods. The results demonstrated
that the rabbit suprarenal glands are paired ellipsoid organs. The right gland was close to the right kidney,
whereas the left gland was located at a distance from the left kidney. The capsule was composed of dense
connective tissue. The parenchyma consisted of three zones: zona glomerulosa, zona fasciculate, and zona
reticularis. The medulla was in the center of the glandular parenchyma. The glands’ radiological and CT
features defined their position relative to the right and left kidneys. The right suprarenal gland was with normal
attenuation. The left suprarenal gland was located at a distance from the left kidney. The US features of the
glands demonstrated variability in darkness and contrast, revealing specific histological features. The MRI
peculiarities of the glands defined them as well visible findings |
Keywords: rabbit, suprarenal glands, imaging modalities, anatomy, histology |