Med. Weter. 79 (10), 525-529, 2023

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Ultrasound monitoring of the regenerative treatment of Biceps Tendonitis and Tenosynovitis in dogs by stem cells injections
Injuries and the overloading of the bicipital muscle tendon in dogs are a common cause of Bicipital Tendinitis and Tenosynovitis (BBT). The aim of the study was to evaluate the advantage of ultrasound monitoring during regenerative treatment of BBT together with treatment assessment by dog owners. 32 dogs of both sexes were used in the study. The dogs were treated with adipose-derived mesenchymal stem cells with platelet-rich plasma (ADMSC + PRP) administered twice in a dose of 0.5 ml (15.0 × 106 cells/ml). The ADMSC + PRP was injected into the tendon sheath of the biceps and 0.5 ml was injected into the brachial joint cavity. During the research, pain evaluation was performed according to the Canine Brief Pain Inventor – Penn CHART (CBPI), ultrasound scans were also performed. Some of the changes in ultrasound images are permanent and the recovery is gradual and incomplete. The research showed a correlation between the results of the ultrasound scans and the owners of the CBPI questionnaire, this was correlated with the effects of regenerative therapy. Studies have shown the regenerative effect of ADMSC + PRP on the tendon sheath and biceps tendon of the brachii after 4 months.
Key words: enthesopathy, biceps brachii tendinopathy, USG, platelet-rich plasma, adipose-derived mesenchymal stem cells.