Med. Weter. 71 (10), 615-618, 2015

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Szalak R., Matysek M., Krawczyk A., Olejarska A., Lalak R., Arciszewski M.B.
Immunoreactivity to the parvalbumin and calbindin D28k in the claustrum and endopiriform nucleus of the
Claustrum (Cl) and endopiriform nucleus (EN) are telencephalic structures present in almost all mammals; however, their exact function(s) remain unknown to date. Parvalbumin (PV) and calbindin-D28k (CB) are calcium-binding proteins (CaBPs) widely present in the central nervous system (CNS) and regulating many important cellular processes, such as the intracellular concentration of calcium, release of neurotransmitters and synaptic conductivity. The aim of the present study was to immunohistochemically determine the distribution patterns of PV and CB in the chinchilla’s Cl and EN. The highest expression of CB was observed in EN, whereas PV-immunoreactive neurons were more abundant in Cl. Three morphological types were identified in neurons expressing PV and CB. PV-immunoreactive neurons belonged to type I and type II, whereas CB-expressing cells were classified as of type I, II and III. It has been concluded that in Cl and EN of the chinchilla, both PV and CB may play a substantial regulatory role modulating the activity of the local neuronal network.
Key words: claustrum, endopiriform nucleus, parvalbumin, calbindin D28k, chinchilla