Medycyna Wet. 56 (2), 103-106, 2000
Samorek-Salamonowicz Elżbieta, Czekaj Hanna, Kozdruń Wojciech, Wilczyńska-Kowal Maria
The influence of immuno-stimulators on sero-conversion after vaccination against Derzsy’s disease in geese
Studies were carried out on three flocks of laying geese marked A, B and C. All the geese were vaccinated against Derzsy’s disease with Dervac before the laying period. The vaccine was administrated twice at 4-week intervals in a dose of 104,3 TCID50. Additionally, birds in flock A received Lydium KLP (0.02 mg/kg, i.m.). In the case of flock B, Levamisol was given in drinking water (2.5 mg/kg) on the day of vaccination and the following day. Control flock C received no immuno-stimulators. All birds were observed during the entire laying season. Twenty blood samples and 15 eggs from each flock were collected to determine the antibody level in serum and egg yolks. The samples were taken on the day of vaccination, at the beginning, middle and end of the laying season. Antibody titres were examined by ELISA and sero-neutralisation (SN) tests. The antibody titres taken at the beginning of the laying season were high both in serum and antibodies in yolk samples. Following this the antibody titres decreased – however in birds which received immuno-stimulators the decrease was less evident. The administration of immuno-stimulators increases antibody production, improves and prolongs humoral response in adult birds as well as guaranteeing the transmission of maternal antibodies to egg yolk, thus protecting progeny against Derzsy’s disease.
Keywords: vaccination against Derzsy’s disease, Lydium KLP, Levamisol, sero-neutralisation test, ELISA.