Medycyna Wet. 62 (9), 1080-1083, 2006
Krzyżowska M., Winicka A., Niemiałtowski M.
Involvement of Fas/FasL proteins in the induction of apoptosis in ectromelia virus infection of BALB/c mice
The present work describes the involvement of Fas/FasL receptors in apoptosis during the pathogenesis of ectromelia virus (ECTV) infection in BALB/c mice. The involvement of Fas/FasL in apoptosis observed during ECTV infection is related to: (a) the influence of ECTV upon the expression of Fas/FasL and subsequent transduction pathways and (b) the specific immunological environment of infected organs and its influence on the functioning of immunocompetent cells.
Keywords: Ectromelia virus, apoptosis, Fas/FasL