Medycyna Wet. 65 (6), 419-421, 2009
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| Jaworska-Adamu J., Szalak R., Matysek M., Szewerniak R. |
| Immunoreactivity of calretinin in the periaqueductal gray matter of the midbrain of chinchillas |
| The purpose of this study was to trace the immunoreactivity of the calcium binding protein calretinin in the periaqueductal gray matter of the midbrain of chinchillas. For this study the midbrains of five sexually mature male chinchillas were used. The immunoreactivity of this protein in this species has never been investigated up till now. The localization of its activity was examined by carrying out peroxidase-antiperoxidase (PAP) reaction using a mouse specific monoclonal antibody against calretinin. An intensive immunostaining for calretitin was observed in all the neurons in the dorsal and dorso-lateral periaqueductal gray matter. The results of the studies obtained suggest a similarity in the distribution of calretitin as seen in the neurons of periaqueductal gray matter of rats. This indicates that calretinin is involved in the regulation of intracellular calcium ion concentration. In this manner it can influence the proper functions of the neurons of the periaqueductal gray matter of the midbrain of the chinchilla. |
| Keywords: chinchilla, periaqueductal gray matter, calretinin |