Medycyna Wet. 66 (1), 5-8, 2010
full text
| Larski Z. |
| Some new data concerning virology and immunology |
| Natural killer cells (NK) traditionally classified as belonging to the innate immune system have many similarities with cytotoxic T lymphocytes. An engineered antibody with a single antigen binding fragment (Fab) capable of recognizing two unrelated proteins. SAP-mediated stable adhesion of antigen-specific T and B cells is crucial for generation long-term immunity. Pharmacological enhancing CD8 T cell memory. Interleukin-21 sustains CD8+T cell effector activity during chronic viral infection. Failures in HIV-vaccine development. |
| Keywords: NK cells, two-in-one antibody, T-B cell interaction, T cell memory, IL-21, HIV vaccine |