Medycyna Wet. 67 (6), 363-367, 2011
| Larski Z. |
| Some new data concerning virology, prions and immunology |
| Rinderpest - the fint infectious animai disease eradicated in the world. Size-based transmission of aggregates creates phenotypic diversity within a prion population. Prions are an unususal from of epigenetics. Origins of prions. Prion-like behaviour of amyloid-β. Limiting chronic pulmonary neutrophilic inflammation by leukotriene A4 hydrolase. Cigarette smoke selectively inhibits this activity. Danger signals guide neutrophils to the sites of sterile inflammation. Self-reneval of mature T reg is a major mechanism of their maintenance in vivo. Sublineage of CD8+T reg is esential regulatory element of the lmmune response and a guarantor of self tolerance. Suppression of antitumbr immunity by stromal cells expressing fibroblast activation protein-α. |
| Keywords: prions, neutrophilic, CD8+T reg, inflammation, antitumor immunity |