Medycyna Wet. 67 (7), 458-461, 2011
Olech M., Kuźmak J.
Infections with small ruminant lentiviruses: updated facts and questions
Small ruminant lentiviruses (SRLV), that is, caprine arthritis-encephalitis virus (CAEV) of goats and maedi-visna virus (MVV) of sheep, are two closely related retroviruses that cause chronic inflammatory disease. SRLV infections are distributed throughout most countries of the world, particularly in Europe, and are characterized by an insidious onset and slow progression. Infection is usually diagnosed by serological testing. The fact that caprine and ovine lentivirus sequences are interspersed within both species supports the existence of cross-species transmission. This paper brings together current information regarding possible impact of genetic diversity and cross-species infection on the effectiveness of serological tests and identifies future use of vaccination
Keywords: small ruminant, lentiviruses, caprine arthritis-encephalitis virus, maedi-visna virus, cross-species transmission