Med. Weter. 75 (5), 287-292, 2019
full text

| EWA KWIT, EWELINA BIGORAJ, ARTUR RZEŻUTKA |
| Myxomatosis, a continually dangerous viral disease of rabbits: current state of knowledge |
| Myxomatosis is a highly infectious viral disease of rabbits. Myxoma virus (MYXV) is not pathogenic to
other animal species except for rabbits and hares. In Poland, outbreaks of myxomatosis mainly occur on
small-scale size rabbit farms in which specific immunoprophylaxis is not carried out. A typical nodular form
of the disease is characterized by swelling and large myxomas over the whole body as well as by lung infection
which is associated with atypical myxomatosis. However, differences in the virulence of MYXV strains are
observed. They arise from a better adaptation of the virus to the rabbit host and they may also be related to the
modulation of cellular response by infected animals. In fact, the changes observed in the MYXV genome do not
result in the emergence of other novel virus strains than those currently circulating in the rabbit population.
In addition, all previously detected strains are characterized by high phylogenetic relatedness.. |
| Key words: Myxomatosis, myxoma virus, rabbits |