Med. Weter. 81
full text
| BEATA ABRAMOWICZ, ŁUKASZ KUREK, PAVOL MUDROŇ, CSILLA TÓTHOVÁ, MATEUSZ MICHALIK, KLAUDIA LUBAS, RENATA URBAN-CHMIEL |
| Diagnosis of liver diseases using ceruloplasmin – a preliminary study |
| The diagnosis of liver diseases currently involves a full clinical examination, an assessment of haematological and biochemical blood parameters, an ultrasound examination, and a biopsy in the case of fatty liver degeneration. Although these tests provide information on the hepatic function, there is a need for a universally applicable marker to diagnose liver disorders in cattle. This study aimed to present the cases of cows with suspected hepatitis and to determine the possibility of assessing the effectiveness of treatment based on preliminary haematological and biochemical blood tests. The tests were performed on tie-stall dairy cattle farms. All diseased animals (16) exhibited a periodic loss of appetite, impaired feed intake, diarrhoea and reduced milk yield. The animals were initially divided into groups of diseased animals (group I) and healthy animals (group II). Based on the authors’ own observations and the therapy efficacy, the initially obtained blood test results were divided into two subgroups (cured animals – group Ia, and animals removed from the herd – group Ib). The blood parameters were examined, including RBC, Hgb, Hct, WBC, GGTP activity and Tbil, Chol-T, urea, Cu, Fe and Cp concentrations. The control group animals exhibited the lowest Cp concentration, whereas the group Ib showed the highest concentration. Statistically significant differences were observed among all groups. The authors suggest that Cp could be a valuable parameter for identifying difficult-to-treat patients during routine screening tests and propose that it be incorporated into the basic liver disease test panels. |
| Keywords: Liver diseases, dairy cattle, ceruloplasmin |